The Traditional Plant Treatment, Sambucus nigra (elder), Exhibits Insulin-Like and Insulin-Releasing Actions In Vitro
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چکیده
منابع مشابه
The traditional plant, Andrographis paniculata (Sambiloto), exhibits insulin-releasing actions in vitro.
AIM to examine the effect of A.paniculata on pancreatic b-cells. METHODS sixty minutes incubation of BRIN-BD11 in Modified Kreb-Ringer Solution containing 16.7 mM glucose (KRB-3) + 0.625 - 2.5 mg/mL A.paniculata evoked 1.7 - 3.73 fold of insulin secretion compared to 16.7 mM glucose only (p = 0.003 - p < 0.001). RESULTS compared to the effect of 100 mM glibenclamide, 60 minutes incubation o...
متن کاملInsulin-releasing and insulin-like activity of the traditional anti-diabetic plant Coriandrum sativum (coriander).
Coriandrum sativum (coriander) has been documented as a traditional treatment of diabetes. In the present study, coriander incorporated into the diet (62.5 g/kg) and drinking water (2.5 g/l, prepared by 15 min decoction) reduced hyperglycaemia of streptozotocin-diabetic mice. An aqueous extract of coriander (1 mg/ml) increased 2-deoxyglucose transport (1.6-fold), glucose oxidation (1.4-fold) an...
متن کاملSambucus nigra (Elderberry) Monograph
Introduction Sambucus nigra, or European elder, is a tall tree-like shrub, native to Europe, Asia, and North Africa, and naturalized in the United States. Various parts of the elder have long been used in traditional medicine as a diaphoretic, diuretic, astringent, laxative, and emetic. The berries were used traditionally as a food to make elderberry wine and pies, and as a flavoring or dye. Cu...
متن کاملAntidepressant activities of Sambucus ebulus and Sambucus nigra.
OBJECTIVE Many pharmacological activities have been reported in Sambucus (S.) genus. The aim of present study was to investigate antidepressant activities of different parts of S. ebulus and S. nigra. MATERIALS AND METHODS Antidepressant activity of methanolic extracts were evaluated by forced swimming test (FST) and tail suspension tests (TST) in male Swiss albino mice. RESULTS Extracts sh...
متن کاملThe Insulin-like Growth Factor-1 (G>A) and 5,10-methylenetetrahydrofolate Reductase (C677T) Gene Variants and the Serum Levels of Insulin-like Growth Factor-1, Insulin, and Homeostasis Model Assessment in Patients with Acne Vulgaris
Background & Objective: To find an association between gene variants of insulin-like growth factor-1 (IGF-1) and 5,10-methylenetetrahydrofolate reductase (MTHFR) with the risk of acne vulgaris (AV). Methods: In a case-control study, we investigated 150 AV patients and 148 healthy individuals (aged 18-25 years) for the IGF-1 G>A and MTHFR C677T polymorphis...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2000
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/130.1.15